Free clearance Lidocaine HCl CAS 73-78-9 lidocaine Powder Lidocaine base free sample USA warehouse 
| Common Name | Lidocaine hydrochloride / Lidocaine HCl | ||
|---|---|---|---|
| CAS Number | 73-78-9 | Molecular Weight | 270.798 |
| Flash Point | 166ºC | Boiling Point | 350.8ºC at 760 mmHg |
| Molecular Formula | C14H23ClN2O | Melting Point | 80-82°C |
Description:
Usage: Lidocaine (Alphacaine)is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. [1] Histamine is responsible for many features of allergic reactions. Lidocaine (Alphacaine)is a second-generation antihistamine agent closely st
Usage: antihypertensive
Usage: Anticonvulsant
Lidocaine,xylocaine, or lignocaine is a common local anesthetic and class-1b antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning, and pain from skin inflammations, injected as a dental anesthetic, or used as a local anesthetic for minor surgery.
| Anesthetic / Pain Killer | |||
| Tetracaine Base | 94-24-6 | Prilocaine hydrochloride | |
| Tetracaine hydrochloride | 136-47-0 | Proparacaine hydrochloride | |
| Lidocaine hydrochloride | 73-78-9 | Pramoxine hydrochloride | |
| Linocaine Base | 137-58-6 | Procainamide hydrochloride | |
| Benzocaine hydrochloride | 23239-88-5 | Ropivacaine hydrochloride | |
| Benzocaine Base | 94-09-7 | Articaine hydrochloride | |
| Procaine | 59-46-1 | Bupivacaine | |
| Procaine hydrochloride | 1951/5/8 | Mepivacaine hydrochloride/Carbocaine | |
| Prilocaine | 721-50-6 | dibucaine hydrochloride | |
Procaine hydrochloride, also called Novocain, or Novocaine, synthetic organic compound used in medicine as a local anesthetic. Introduced in 1905 under the trade name Novocaine, it became the first and best-known substitute for cocaine in local anesthesia. Generally used in a 1 to 10 percent saline solution, procaine hydrochloride is administered by injection for infiltration (area flooding as in dental anesthesia), nerve-block, spinal, and caudal anesthesia. Unlike cocaine, procaine is not toxic, addicting, or irritating.It has been displaced somewhat by the chemically related drugs lidocaine and mepivacaine, which produce prompter, more intense anesthesia.
Procaine is an anesthetic agent indicated for production of local or regional anesthesia, particularly for oral surgery. Procaine (like cocaine) has the advantage of constricting blood vessels which reduces bleeding, unlike other local anesthetics like lidocaine. Procaine is an ester anesthetic. It is metabolized in the plasma by the enzyme pseudocholinesterase through hydrolysis into para-aminobenzoic acid (PABA), which is then excreted by the kidneys into the urine.
Procaine acts mainly by inhibiting sodium influx through voltage gated sodium channels in the neuronal cell membrane of peripheral nerves. When the influx of sodium is interrupted, an action potential cannot arise and signal conduction is thus inhibited. The receptor site is thought to be located at the cytoplasmic (inner) portion of the sodium channel. Procaine has also been shown to bind or antagonize the function of N-methyl-D-aspartate (NMDA) receptors as well as nicotinic acetylcholine receptors and the serotonin receptor-ion channel complex.
Items | Standard | Results of analysis |
Appearance | White to class white powder | Class white powder |
Solubility | Almost insoluble in water, soluble in dimethyl sulfoxide, slightly soluble in dichloromethane | Conforms |
Speicific rotation | +78.0°~+84.0° | +82.3° |
Ordinary impurities (Do not calculate isomer A+C) | Single impurity≤0.15% | 0.03% |
Total impurities≤1.0% | 0.09% | |
Calculate isomer | A≤0.15% | 0.02% |
B≤0.1% | Not detected | |
C≤0.1% | Not detected | |
Loss on drying | ≤0.5% | 0.31% |
Residue on ignition | ≤0.1% | Conforms |
Heavy metal | 20ppm | Conforms |
Assay | 97.5%-102.0% | 99.8% |
Conclusion :The test results conform with USP36. | ||
Shanghai Biolang Biotechnology Co.,Ltd located in the Shanghai Zhangjiang BioPark where is a High-tech Medical industry of China,specilize in producing and developing Sarms, peptide and antipsychotics raw materials in distributing the products of our own company and affiliated enterprises. We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and others places.Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the 25 years.
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